| Mild cognitive impairment in medical inpatients: the Mini-Mental State Examination is a promising screening tool. | |
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MedLine Citation:
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PMID: 20375507 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To assess the prevalence of mild cognitive impairment (MCI) in medical inpatients aged 55-85 years without known cognitive deficits, and how often ward physicians mentioned MCI in their discharge notes. Moreover, we aimed to identify variables associated with MCI and to assess the sensitivity and specificity of the Mini-Mental State Examination (MMSE) for MCI. METHODS: Two neuropsychologists administered a 60-min battery of validated tests to evaluate different cognitive domains. The diagnosis of MCI was based on a prespecified algorithm. The sensitivity and specificity of the MMSE for MCI were calculated. RESULTS: Fifteen patients showed a normal cognitive profile (21.4%), while 55 patients (78.6%) showed MCI. Ward physicians, blinded to the results of the neuropsychological evaluation, did not mention MCI in their discharge notes of any of the evaluated patients. The only variable independently associated with MCI was the MMSE. A MMSE score of < or =28 showed a sensitivity of 85.5% and a specificity of 66.7% for MCI. CONCLUSION: MCI is frequent albeit overlooked in elderly medical inpatients without previously known cognitive deficits. In view of therapies preventing the progression of MCI to dementia, MCI screening will be crucial. The MMSE represents a promising screening tool for MCI in medical inpatients. |
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Authors:
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G M De Marchis; G Foderaro; J Jemora; F Zanchi; A Altobianchi; E Biglia; F M Conti; R Monotti; G Mombelli |
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Publication Detail:
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Type: Journal Article Date: 2010-04-06 |
Journal Detail:
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Title: Dementia and geriatric cognitive disorders Volume: 29 ISSN: 1421-9824 ISO Abbreviation: Dement Geriatr Cogn Disord Publication Date: 2010 |
Date Detail:
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Created Date: 2010-04-16 Completed Date: 2010-07-09 Revised Date: 2011-01-11 |
Medline Journal Info:
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Nlm Unique ID: 9705200 Medline TA: Dement Geriatr Cogn Disord Country: Switzerland |
Other Details:
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Languages: eng Pagination: 259-64 Citation Subset: IM |
Copyright Information:
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2010 S. Karger AG, Basel. |
Affiliation:
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Department of Internal Medicine, Ospedale La Carità, Locarno, Switzerland. gian-marco.demarchis@insel.ch |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Aged Aged, 80 and over Cognition Disorders / diagnosis*, epidemiology, psychology* Comorbidity Education Female Humans Inpatients / psychology Male Memory / physiology Middle Aged Neuropsychological Tests* Odds Ratio Risk Factors Switzerland / epidemiology |
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