Document Detail


Migration, particles, and fluid pressure. A discussion of causes of prosthetic loosening.
MedLine Citation:
PMID:  9678035     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Distal migration of the femoral component of a total hip replacement by as little as 0.33 mm during the first 6 postoperative months is predictive of the need for revision many years later. Because the fate of the prostheses is defined so early, it is unlikely that wear particles initiate loosening. However, the progression from the stage of early migration to clinical loosening has unknown causes, of which particles may be one. Slight instability associated with migration will lead to locally high fluid pressures surrounding the migrating prosthesis. Recent experiments applied a moderate fluid pressure to an implant to bone interface. This induced osteocyte death near the implant and subsequent bone resorption. Thus, there is evidence that fluid pressure and ensuing flow could be a main cause of not only pain, but also osteolysis necessitating revision.
Authors:
P Aspenberg; H Van der Vis
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Clinical orthopaedics and related research     Volume:  -     ISSN:  0009-921X     ISO Abbreviation:  Clin. Orthop. Relat. Res.     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-08-26     Completed Date:  1998-08-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0075674     Medline TA:  Clin Orthop Relat Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  75-80     Citation Subset:  AIM; IM    
Affiliation:
Department of Orthopedics, Lund University Hospital, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Animals
Arthroplasty, Replacement, Hip
Bone Resorption
Foreign Bodies
Hip Joint
Hip Prosthesis*
Humans
Pressure
Prosthesis Failure*
Reoperation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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