Document Detail

Migration of the nucleus and cytoplasm along the pseudopodium of the differentiated neuroblastoma cell
MedLine Citation:
PMID:  3438937     Owner:  NLM     Status:  MEDLINE    
Motility of neuroblastoma cells in the culture of cell line C-1300, clone N-18-A was investigated microcinematographically. In the course of morphological differentiation of the cells, after cytochalasin B treatment (1.8 mkg/ml for 24 hours), in some differentiated cells a special type of movement of the cytoplasmic mass together with the nucleus along elongated pseudopodia was detected. Such a type of movement has never been described. Sometimes, a shift in the nucleus position resulted in the complete change or reversion of cell polarity. The phenomenon of cell nucleus displacement relative to the cell configuration or reversion of the cell polarity can possibly play an important functional role for neural cells.
O Iu Ivanova; L V Domnina; Iu M Vasil'ev; I M Gel'fand
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Tsitologiia     Volume:  29     ISSN:  0041-3771     ISO Abbreviation:  Tsitologiia     Publication Date:  1987 Nov 
Date Detail:
Created Date:  1988-03-25     Completed Date:  1988-03-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0417363     Medline TA:  Tsitologiia     Country:  USSR    
Other Details:
Languages:  rus     Pagination:  1307-9     Citation Subset:  IM    
Vernacular Title:
Migratsiia iadra i tsitoplazmy vdol' udlinennogo otrostka differentsirovannoĭ kletki neĭroblastomy.
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MeSH Terms
Cell Line
Cell Movement / drug effects
Cell Nucleus / drug effects,  ultrastructure*
Cell Transformation, Neoplastic / drug effects,  ultrastructure*
Cytochalasin B / pharmacology
Cytoplasm / drug effects,  ultrastructure*
Neuroblastoma / ultrastructure*
Pseudopodia / drug effects,  ultrastructure*
Tumor Cells, Cultured
Reg. No./Substance:
14930-96-2/Cytochalasin B

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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