Document Detail

Migrainous syndrome with CSF pleocytosis. SPECT findings.
MedLine Citation:
PMID:  9329234     Owner:  NLM     Status:  MEDLINE    
Brain single photon emission computed tomography (SPECT) findings are described in four adult patients with the transient syndrome of headache with neurological deficits and cerebrospinal fluid (CSF) pleocytosis. Focal deficits consisted of right-sided hemisensory changes with or without motor dysphasia or dysarthric speech (n = 4) and confusional episodes (n = 1). All patients had a CSF pleocytosis (with a mean of 309 cells/mm3 on the first spinal tap; range 75 to 590) and an elevated total protein (mean 130.5 mg/dL; range 70 to 193). The EEG showed excessive focal slowing (n = 2). A technetium Tc 99m hexamethyl propylenamine oxime (HMPAO) brain SPECT was performed during a symptom-free period, within 8 and 25 days after the onset of symptoms (n = 4). Three patients showed a decreased tracer uptake in the anterior left hemisphere, topographically consistent with the neurological deficits and EEG slowing. One patient showed no abnormalities. These findings indicate either focally impaired neuronal metabolism or hypoperfusion in regional cerebral blood flow, which could bear some relationship with the clinical features. The possibility that SPECT abnormalities may represent an epiphenomenon was also considered.
A B Caminero; J A Pareja; J Arpa; F Vivancos; F Palomo; J Coya
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Headache     Volume:  37     ISSN:  0017-8748     ISO Abbreviation:  Headache     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1997-11-05     Completed Date:  1997-11-05     Revised Date:  2009-02-02    
Medline Journal Info:
Nlm Unique ID:  2985091R     Medline TA:  Headache     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  511-5     Citation Subset:  IM    
Unidad de Neurología, Hospital Ntra. Sra. de Sonsoles, Avila, Spain.
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MeSH Terms
Migraine Disorders / cerebrospinal fluid*,  physiopathology,  radionuclide imaging*
Tomography, Emission-Computed, Single-Photon*
Comment In:
Headache. 1998 Jun;38(6):481-2   [PMID:  9664757 ]

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