Document Detail


Migraine and vasodepressor syncope in a large family.
MedLine Citation:
PMID:  19876431     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We evaluated a 47-year-old woman for recurrent migraine and syncope. The patient had 7 children (not examined by the authors), all of whom also experienced migraine and syncope. The patient's father, now deceased, had reportedly experienced migraine and episodes of feeling faint. All 5 of the patient's siblings reported migraine, and 4 of the 5 reported syncope. The case of our patient, which we discuss herein, suggests a genetic link between these 2 conditions, both of which include vascular dysregulation in their pathogenesis. To our knowledge, the medical literature contains no previous description of familial associations of combined migraine and syncope.
Authors:
Robert D Paisley; Harvinder S Arora; Alireza Nazeri; Ali Massumi; Mehdi Razavi
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital     Volume:  36     ISSN:  1526-6702     ISO Abbreviation:  Tex Heart Inst J     Publication Date:  2009  
Date Detail:
Created Date:  2009-10-30     Completed Date:  2010-02-01     Revised Date:  2010-09-28    
Medline Journal Info:
Nlm Unique ID:  8214622     Medline TA:  Tex Heart Inst J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  468-9     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Texas Heart Institute at St. Luke's Episcopal Hospital, and University of Texas Medical School at Houston, Houston, Texas 77030, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Child
Child, Preschool
Female
Genetic Predisposition to Disease
Humans
Male
Middle Aged
Migraine Disorders / diagnosis,  drug therapy,  genetics*
Pedigree
Recurrence
Risk Factors
Syncope, Vasovagal / diagnosis,  drug therapy,  genetics*
Young Adult
Comments/Corrections

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