Document Detail


Migraine-mimicking headache and sickle cell disease: a transcranial Doppler study.
MedLine Citation:
PMID:  16686906     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Headache occurs in sickle cell disease (SCD), but its characteristics and frequency have not previously been studied. Our aim was to study patterns of headache in adults with SCD and to correlate its presence with blood flow velocities measured by transcranial Doppler (TCD) and with brain magnetic resonance imaging (MRI) abnormalities. We studied 56 adults with SCD. Twenty-eight patients (50%) had severe and frequent headaches. In 20 patients (35.7%) the headache met the International Headache Society criteria for migraine without aura. Patients with frequent and severe headache presented TCD velocities significantly higher than those without headache, or with milder headache. No correlation was found between headache and abnormalities in brain MRI. A migraine-mimicking headache occurs in SCD but we should not understand it as a primary headache because the blood flow abnormalities secondary to SCD detected by TCD seem to play an important role in these patients.
Authors:
G S Silva; P Vicari; M S Figueiredo; H C Junior; M H Idagawa; A R Massaro
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Cephalalgia : an international journal of headache     Volume:  26     ISSN:  0333-1024     ISO Abbreviation:  Cephalalgia     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-11     Completed Date:  2006-08-01     Revised Date:  2008-02-11    
Medline Journal Info:
Nlm Unique ID:  8200710     Medline TA:  Cephalalgia     Country:  England    
Other Details:
Languages:  eng     Pagination:  678-83     Citation Subset:  IM    
Affiliation:
Department of Neurology, Universidade Federal de Sao Paulo, São Paulo, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Anemia, Sickle Cell / complications*,  diagnosis*,  ultrasonography
Diagnosis, Differential
Female
Headache / diagnosis,  etiology*,  ultrasonography*
Humans
Male
Middle Aged
Migraine Disorders / diagnosis,  etiology*,  ultrasonography*
Reproducibility of Results
Sensitivity and Specificity
Ultrasonography, Doppler, Transcranial / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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