Document Detail

Migraine, stroke and epilepsy: underlying and interrelated causes, diagnosis and treatment.
MedLine Citation:
PMID:  23417269     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Migraine, epilepsy and stroke are highly prevalent neurological disorders, often comorbid. They share diverse pathophysiological mechanisms that explain the use of similar drugs on certain occasions (i.e., the use of antiepileptic drugs in migraine prevention). Migraine with aura represents a risk for ischemic stroke, and avoiding contraceptives, tobacco use, and ergot alkaloids should be advised in those patients. Epilepsy bears a bidirectional relationship with headache. Only three entities are considered as seizure-related headaches: migraine-triggered seizure (migralepsy), hemicrania epileptica, and post-ictal headache. Topiramate (100-200 mg daily) and valproic acid (500-1,000 mg daily) are first-line drugs in migraine prevention, while older antiepileptics have no use in this setting. Stroke is the most common cause of symptomatic epilepsy in the adult. Therapy with lamotrigine, gabapentine, and levetiracetam is advised in late-onset (2 weeks after stroke) stroke-seizures, while early-onset seizures usually do not require therapy.
Aida Rodriguez-Sainz; Ana Pinedo-Brochado; Jose L Sánchez-Menoyo; Javier Ruiz-Ojeda; Ines Escalza-Cortina; Juan Carlos Garcia-Monco
Related Documents :
25331059 - Stemming the tide of drug-resistant neisseria gonorrhoeae: the need for an individualiz...
25493429 - Shifts in mycobacterial populations and emerging drug-resistance in west and central af...
22712739 - Pathophysiologic cascades in ischemic stroke.
25016619 - Schedule of controlled substances: placement of tramadol into schedule iv. final rule.
25378409 - Multiple drugs compete for transport via the p. falciparum chloroquine resistance trans...
25315499 - Multi-drug delivery system based on alginate/calcium carbonate hybrid nanoparticles for...
12849119 - Therapeutic hypothermia for acute stroke.
7058359 - Effect of repeated succinylcholine injections on heart rate following intramuscularly a...
21232779 - Ccr5 antibodies hgs004 and hgs101 preferentially inhibit drug-bound ccr5 infection and ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current treatment options in cardiovascular medicine     Volume:  15     ISSN:  1092-8464     ISO Abbreviation:  Curr Treat Options Cardiovasc Med     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-05-10     Completed Date:  2013-05-13     Revised Date:  2013-07-25    
Medline Journal Info:
Nlm Unique ID:  9815942     Medline TA:  Curr Treat Options Cardiovasc Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  322-34     Citation Subset:  -    
Department of Neurology, Hospital de Galdakao-Usansolo, 48960, Vizcaya, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The impact of alcohol intoxication in patients admitted due to assault at an Australian major trauma...
Next Document:  Bats, balls, and substitution sensitivity: cognitive misers are no happy fools.