| Midtrimester abortion using vaginal misoprostol for women with three or more prior cesarean deliveries. | |
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MedLine Citation:
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PMID: 20362989 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the safety and efficacy of vaginal misoprostol for second-trimester abortion in women with 3 or more prior cesarean deliveries. METHODS: This study was conducted with 138 women who needed pregnancy termination between 13 and 26 gestational weeks, 31 with 3 or more previous cesarean deliveries and 107 with no uterine scars (the controls). Misoprostol was inserted in the vagina every 6 hours until regular contractions or products of conception appeared, a 200-microg tablet for the first 24 hours and 2 tablets thereafter. The outcomes assessed were successful vaginal abortion, hemorrhage requiring blood transfusion, incomplete abortion, and uterine rupture. RESULTS: A vaginal abortion occurred in 28 women (90.3%) in the study group and 107 (100%) in the control group (P=0.01). There were no significant differences in the prevalence of the other assessed outcomes. CONCLUSION: Vaginal misoprostol appears to be safe and acceptably effective for second-trimester pregnancy termination in women with 3 or more previous cesarean deliveries. |
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Authors:
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Muhammad Fawzy; El-Said Abdel-Hady |
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Publication Detail:
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Type: Journal Article Date: 2010-04-02 |
Journal Detail:
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Title: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Volume: 110 ISSN: 1879-3479 ISO Abbreviation: Int J Gynaecol Obstet Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-08-04 Completed Date: 2010-11-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0210174 Medline TA: Int J Gynaecol Obstet Country: Ireland |
Other Details:
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Languages: eng Pagination: 50-2 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2010 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Mansoura, Egypt. mmfawzy@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortifacient Agents, Nonsteroidal
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administration & dosage,
adverse effects,
therapeutic use* Abortion, Induced / methods* Administration, Intravaginal Adult Case-Control Studies Cesarean Section / adverse effects Cicatrix / complications*, etiology Female Humans Misoprostol / administration & dosage, adverse effects, therapeutic use* Pregnancy Pregnancy Trimester, Second Treatment Outcome Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Abortifacient Agents, Nonsteroidal; 59122-46-2/Misoprostol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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