| Midterm reversible failure in trabeculectomies with adjunctive mitomycin-C. | |
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MedLine Citation:
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PMID: 9427985 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND OBJECTIVES: Trabeculectomies usually fail early (< 21 days) or late (> 6 months) when no antifibrotic agent is used. Failure is uncommon during the midterm period, between 3 weeks and 6 months. The purpose of this study is to verify the incidence of failure of trabeculectomies with mitomycin-C (MMC) during the midterm period and to evaluate the safety and efficacy of laser suture lysis (LSL) for reversing it. PATIENTS AND METHODS: The authors reviewed the records of 130 consecutive patients who underwent trabeculectomy with adjunctive MMC. RESULTS: Fourteen patients (15 eyes) had increased intraocular pressure (IOP), between 21 and 185 days (median 41 days). LSL was effective in decreasing the IOP to acceptable levels in 10 (66.6%) of the 15 eyes. No complications related to LSL were noticed. CONCLUSION: The reversibility of midterm failure seems to be a unique feature of trabeculectomies with MMC. |
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Authors:
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N Kasahara; T J Smith; S A Sibayan; M H Montenegro; R B Simmons; R J Simmons |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Ophthalmic surgery and lasers Volume: 28 ISSN: 1082-3069 ISO Abbreviation: Ophthalmic Surg Lasers Publication Date: 1997 Dec |
Date Detail:
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Created Date: 1998-02-23 Completed Date: 1998-02-23 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9517132 Medline TA: Ophthalmic Surg Lasers Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 986-91 Citation Subset: IM |
Affiliation:
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New England Glaucoma Research Foundation, Schepens Eye Research Institute. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Antibiotics, Antineoplastic / administration & dosage, adverse effects* Chemotherapy, Adjuvant Female Follow-Up Studies Glaucoma / therapy* Humans Intraocular Pressure Laser Therapy Male Middle Aged Mitomycin / administration & dosage, adverse effects* Ocular Hypertension / etiology, surgery* Ophthalmic Solutions Retrospective Studies Safety Suture Techniques Trabeculectomy / adverse effects* Treatment Failure |
| Chemical | |
Reg. No./Substance:
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0/Antibiotics, Antineoplastic; 0/Ophthalmic Solutions; 50-07-7/Mitomycin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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