Document Detail

Midterm results of the neonatal arterial switch operation. A review.
MedLine Citation:
PMID:  10532208     Owner:  NLM     Status:  MEDLINE    
Complete transposition of the great arteries is a relatively common anomaly, which comprises 5 to 7% of all instances of cardiac malformations. Given the decreasing mortality rates associated with a neonatal arterial switch operation and the unacceptable morbidity associated with atrial baffle operations, it is reasonable to accept this operation as the procedure of choice for the treatment of the complete transposition of the great arteries. It represents a major improvement since it does not introduce any additional intracardiac anomaly, restores the left ventricle to its natural systemic function, and maintains the sinus node function. Long-term survival exceeds 90%. Midterm general health status is encouraging. To date, there have been limited long-term follow-up studies after a neonatal arterial switch operation, although the intermediate data are promising. It will be necessary to determine whether the theorized benefits of the anatomic repair are realized, since experience is limited to the last 15 years. Translocation of the coronary arteries remains one of the most difficult aspects of the operation and late mortality appears to coincide with coronary artery events with sudden death secondary to acute myocardial infarction being reported in 1-2% of hospital survivors. Supravalvar pulmonary stenosis, neoaortic root dilation and valvar regurgitation, bronchopulmonary collateral arteries, coronary insufficiency, and myocardial perfusion abnormalities are other specific areas which require close observation and further investigation.
M M Massin
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of cardiovascular surgery     Volume:  40     ISSN:  0021-9509     ISO Abbreviation:  J Cardiovasc Surg (Torino)     Publication Date:  1999 Aug 
Date Detail:
Created Date:  1999-10-28     Completed Date:  1999-10-28     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0066127     Medline TA:  J Cardiovasc Surg (Torino)     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  517-22     Citation Subset:  IM    
Division of Pediatric Cardiology, University of Liège, Belgium.
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MeSH Terms
Cause of Death
Death, Sudden, Cardiac / epidemiology
Follow-Up Studies
Hospital Mortality
Infant, Newborn
Postoperative Complications / mortality*
Survival Rate
Transposition of Great Vessels / mortality,  surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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