| Midterm outcome of ultrasound-guided alcohol gel sclerotherapy for symptomatic leiomyoma. | |
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MedLine Citation:
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PMID: 20733188 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this study was to describe the outcome of ultrasound-guided ethanol gel sclerotherapy of myomatous nodules 1 to 18 months after treatment. METHODS: A total of 118 consecutive patients with a diagnosis of symptomatic leiomyomas referred for ethanol gel sclerotherapy were studied between November 2005 and July 2007. Clinical (self-administered symptom questionnaire) and ultrasound follow-ups were done 1 to 2, 6 to 8, and 12 to 18 months after the procedure. RESULTS: The mean baseline volumes +/- SD were 223.3 +/- 158.3 cm(3) for the uterus and 68.4 +/- 110.5 cm(3) for the dominant fibroid. The most common adverse reaction in the immediate postoperative period was pelvic pain in 27.1% of the patients, but 58.4% had no reactions. After 12 months, a 29.5% reduction in uterine volume was observed in 64.7% of the patients. A 55.5% reduction in dominant fibroid volume was observed in 82.8% of the patients. Pelvic pain improved in 29.8% of the sample, dysmenorrhea in 51.7%, and menstrual flow in 39%. Most patients (77%) reported being satisfied or very satisfied with the treatment. CONCLUSIONS: The results suggest that ethanol gel sclerotherapy is a safe, conservative alternative for treating symptomatic uterine leiomyomas. Further randomized studies are necessary to determine the suitability and indications of this procedure in comparison to other minimally invasive techniques. |
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Authors:
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Lucilo Avila Pessoa; Fernando Gurgel; Mirela Avila; Maria da Conceição Souto Maior; Valeria Maria Bezerra Silva |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine Volume: 29 ISSN: 1550-9613 ISO Abbreviation: J Ultrasound Med Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-24 Completed Date: 2011-01-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8211547 Medline TA: J Ultrasound Med Country: United States |
Other Details:
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Languages: eng Pagination: 1323-30 Citation Subset: IM |
Affiliation:
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Department of Ultrasonography, Centro Diagnóstico Lucilo Avila Júnior, Recife, Brazil. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chi-Square Distribution Ethanol / administration & dosage Female Gels Humans Leiomyoma / therapy*, ultrasonography Middle Aged Questionnaires Sclerotherapy / methods* Treatment Outcome Ultrasonography, Interventional* Uterine Neoplasms / therapy*, ultrasonography |
| Chemical | |
Reg. No./Substance:
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0/Gels; 64-17-5/Ethanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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