| Midterm clinical and angiographic results of radial artery grafts used for myocardial revascularization. | |
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MedLine Citation:
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PMID: 9832694 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the midterm angiographic results of the use of radial artery grafts for myocardial revascularization. METHODS: The first 68 consecutive surviving patients who received a radial artery graft proximally anastomosed to the aorta at our institution were studied again at 5 years (mean 59 +/- 6.5 months) of follow-up; 48 of these patients had previously undergone an early angiographic examination. The response of the radial artery to the endovascular infusion of serotonin was evaluated 1 and 5 years after the operation, and the midterm status of the radial artery graft was correlated with the degree of preoperative stenosis of the target vessel and with calcium-channel blocker therapy. RESULTS: The patency and perfect patency rates of the radial artery grafts 5 years after the operation were 91.9% and 87.0%, respectively. All radial artery grafts that were patent early after the operation remained patent at midterm follow-up, and early parietal irregularities in 7 patients were seen to have disappeared after 5 years. The early propensity toward graft spasm after serotonin challenge was markedly decreased at midterm follow-up. The continued use of calcium-channel antagonists after the first postoperative year did not influence the radial artery graft status, whereas the preoperative severity of the target-vessel stenosis markedly influenced the angiographic results. CONCLUSIONS: The midterm angiographic results of radial artery grafts used for myocardial revascularization are excellent. The correct surgical indication is essential. Continued therapy with calcium-channel antagonists after the first year does not influence the midterm angiographic results. |
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Authors:
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G Possati; M Gaudino; F Alessandrini; N Luciani; F Glieca; C Trani; C Cellini; C Canosa; G Di Sciascio |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The Journal of thoracic and cardiovascular surgery Volume: 116 ISSN: 0022-5223 ISO Abbreviation: J. Thorac. Cardiovasc. Surg. Publication Date: 1998 Dec |
Date Detail:
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Created Date: 1999-01-06 Completed Date: 1999-01-06 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376343 Medline TA: J Thorac Cardiovasc Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1015-21 Citation Subset: AIM; IM |
Affiliation:
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Departments of Cardiac Surgery and Cardiology, Catholic University, and the Department of Cardiology, Campus Biomedico University, Rome, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Calcium Channel Blockers
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therapeutic use Coronary Angiography* Coronary Artery Bypass Coronary Disease / drug therapy, radiography, surgery* Female Follow-Up Studies Free Radical Scavengers / administration & dosage, diagnostic use Humans Infusions, Intra-Arterial Male Middle Aged Myocardial Revascularization* / methods Radial Artery / drug effects, transplantation*, ultrasonography Reoperation Retrospective Studies Serotonin / administration & dosage, diagnostic use Ultrasonography, Doppler Vasoconstriction / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Calcium Channel Blockers; 0/Free Radical Scavengers; 50-67-9/Serotonin |
| Comments/Corrections | |
Comment In:
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J Thorac Cardiovasc Surg. 1999 Jun;117(6):1227-8
[PMID:
10383267
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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