Document Detail

Midterm clinical and angiographic results of radial artery grafts used for myocardial revascularization.
MedLine Citation:
PMID:  9832694     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the midterm angiographic results of the use of radial artery grafts for myocardial revascularization. METHODS: The first 68 consecutive surviving patients who received a radial artery graft proximally anastomosed to the aorta at our institution were studied again at 5 years (mean 59 +/- 6.5 months) of follow-up; 48 of these patients had previously undergone an early angiographic examination. The response of the radial artery to the endovascular infusion of serotonin was evaluated 1 and 5 years after the operation, and the midterm status of the radial artery graft was correlated with the degree of preoperative stenosis of the target vessel and with calcium-channel blocker therapy. RESULTS: The patency and perfect patency rates of the radial artery grafts 5 years after the operation were 91.9% and 87.0%, respectively. All radial artery grafts that were patent early after the operation remained patent at midterm follow-up, and early parietal irregularities in 7 patients were seen to have disappeared after 5 years. The early propensity toward graft spasm after serotonin challenge was markedly decreased at midterm follow-up. The continued use of calcium-channel antagonists after the first postoperative year did not influence the radial artery graft status, whereas the preoperative severity of the target-vessel stenosis markedly influenced the angiographic results. CONCLUSIONS: The midterm angiographic results of radial artery grafts used for myocardial revascularization are excellent. The correct surgical indication is essential. Continued therapy with calcium-channel antagonists after the first year does not influence the midterm angiographic results.
G Possati; M Gaudino; F Alessandrini; N Luciani; F Glieca; C Trani; C Cellini; C Canosa; G Di Sciascio
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Journal of thoracic and cardiovascular surgery     Volume:  116     ISSN:  0022-5223     ISO Abbreviation:  J. Thorac. Cardiovasc. Surg.     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1999-01-06     Completed Date:  1999-01-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376343     Medline TA:  J Thorac Cardiovasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1015-21     Citation Subset:  AIM; IM    
Departments of Cardiac Surgery and Cardiology, Catholic University, and the Department of Cardiology, Campus Biomedico University, Rome, Italy.
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MeSH Terms
Calcium Channel Blockers / therapeutic use
Coronary Angiography*
Coronary Artery Bypass
Coronary Disease / drug therapy,  radiography,  surgery*
Follow-Up Studies
Free Radical Scavengers / administration & dosage,  diagnostic use
Infusions, Intra-Arterial
Middle Aged
Myocardial Revascularization* / methods
Radial Artery / drug effects,  transplantation*,  ultrasonography
Retrospective Studies
Serotonin / administration & dosage,  diagnostic use
Ultrasonography, Doppler
Vasoconstriction / drug effects
Reg. No./Substance:
0/Calcium Channel Blockers; 0/Free Radical Scavengers; 50-67-9/Serotonin
Comment In:
J Thorac Cardiovasc Surg. 1999 Jun;117(6):1227-8   [PMID:  10383267 ]

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