Document Detail


Midregional pro-A-type natriuretic peptide for the evaluation of exercise intolerance.
MedLine Citation:
PMID:  20034689     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The aim of this study was to determine the accuracy of midregional pro-A-type natriuretic peptide (MR-proANP) for the identification of a cardiocirculatory exercise limitation (CL) as assessed by cardiopulmonary exercise testing (CPET) and to compare it to B-type natriuretic peptide (BNP). Among 94 patients with CPET data fulfilling criteria for appropriate effort and sufficient diagnostic certainty, 27 (29%) had CL. The areas under the receiver-operator-characteristic curve for MR-proANP and BNP to identify CL were 0.84 and 0.79 respectively (p=0.17). In conclusion, MR-proANP had a comparable accuracy to BNP for the identification of CL and might be a valuable assistance for the differentiation of exercise intolerance.
Authors:
Micha T Maeder; Martin H Brutsche; Andreas Christ; Daniel Staub; Markus Noveanu; Tobias Breidthardt; Nora Schaub; Mihael Potocki; Tobias Reichlin; Nils G Morgenthaler; Andreas Bergmann; Christian Mueller
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Publication Detail:
Type:  Letter; Research Support, Non-U.S. Gov't     Date:  2010-01-19
Journal Detail:
Title:  International journal of cardiology     Volume:  145     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-12-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  326-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.
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