Document Detail


Midline maxillofacial skeleton in human anencephalic fetuses.
MedLine Citation:
PMID:  7918519     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to describe the midline maxillofacial skeleton (the axial skeleton anterior to the sella turcica) in 15 human anencephalic fetuses (14-19 weeks of gestation) by radiography and histology, and to relate the findings to skeletal patterns in the remaining part of the axial skeleton. Four patterns in the maxillofacial skeleton were recognized: normal structures, slightly deformed (6 cases); cleft palate (3 cases); incomplete nasal septum (3 cases); multilocular ethmoid cartilage (3 cases). No association was found between skeletal patterns in the different parts of the axial skeleton. The study demonstrates the existence of a developmental borderline in the anencephalic axial skeleton in the region of the sella turcica. It is presumed that this borderline indicates the boundary between skeletal tissue developed around the notochord (posterior axial skeleton) and the anterior skeletal components derived from neural crest cells.
Authors:
I Kjaer; J W Keeling; N Graem
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association     Volume:  31     ISSN:  1055-6656     ISO Abbreviation:  Cleft Palate Craniofac. J.     Publication Date:  1994 Jul 
Date Detail:
Created Date:  1994-11-16     Completed Date:  1994-11-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9102566     Medline TA:  Cleft Palate Craniofac J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  250-6     Citation Subset:  D; IM    
Affiliation:
Department of Orthodontics, School of Dentistry, University of Copenhagen, Denmark.
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MeSH Terms
Descriptor/Qualifier:
Anencephaly / embryology*,  pathology
Cleft Palate / embryology*
Embryonic and Fetal Development
Ethmoid Bone / abnormalities,  embryology*
Facial Bones / abnormalities*,  embryology*
Gestational Age
Humans
Maxillofacial Development
Nasal Septum / abnormalities,  embryology*
Neural Crest / embryology
Notochord / embryology
Sella Turcica / embryology
Spinal Dysraphism / embryology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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