Document Detail

Middle ear adenoma/carcinoid tumour: a case report and review of the literature.
MedLine Citation:
PMID:  20345079     Owner:  NLM     Status:  MEDLINE    
CASE REPORT: We report a case of a 52-year-old woman, who presented with progressive hearing loss and fullness in the left ear for 3 months. Clinical examination revealed a mass in the left middle ear. Histological examination revealed tumour cells forming gland-like and cribriform structures, as well as compact groups. The nuclei were round and uniform, without atypia or mitotic activity. On immunohistochemical staining, the tumour cells were positive for epithelial (cytokeratins, epithelial membrane antigen) and neuroendocrine (neuron specific enolase, synaptophysin, chromogranin and pancreatic polypeptide) markers.
CONCLUSION: Middle ear adenoma is a benign tumour that is treated by complete surgical removal. Follow-up of the patient is essential in order to detect possible recurrence. The immunohistochemical staining of the present case supports the suggestion that this tumour is best described by the term neuroendocrine adenoma of the middle ear.
N Angouridakis; P Hytiroglou; K Markou; A Bouzakis; V Vital
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Revue de laryngologie - otologie - rhinologie     Volume:  130     ISSN:  0035-1334     ISO Abbreviation:  Rev Laryngol Otol Rhinol (Bord)     Publication Date:  2009  
Date Detail:
Created Date:  2010-03-29     Completed Date:  2010-06-03     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  0414144     Medline TA:  Rev Laryngol Otol Rhinol (Bord)     Country:  France    
Other Details:
Languages:  eng     Pagination:  199-202     Citation Subset:  IM    
University Hospital, Aristotle University Medical School, Department of Otolaryngology/Head & Neck Surgery, AHEPA 54006 Thessaloniki, Greece.
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MeSH Terms
Adenoma* / diagnosis,  surgery
Carcinoid Tumor* / diagnosis,  surgery
Ear Neoplasms* / diagnosis,  surgery
Ear, Middle*
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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