Document Detail

Middle ear adenoma: tumour of mixed mucinous and neuroendocrine differentiation.
MedLine Citation:
PMID:  1890199     Owner:  NLM     Status:  MEDLINE    
Two cases of progressive hearing loss due to middle ear tumours are described. The histological characteristics numbered intraluminal mucin production and neuroendocrine features, as shown by argyrophilia and ultrastructural demonstration of dense core granules. These tumours have been known by many different names, reflecting the controversies relating to their presumed histogenesis and differentiation. The currently preferred designation is middle ear adenoma, and these two cases provide further evidence for dual lines of differentiation.
R J Hale; R F McMahon; J S Whittaker
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  44     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  1991 Aug 
Date Detail:
Created Date:  1991-10-17     Completed Date:  1991-10-17     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  652-4     Citation Subset:  AIM; IM    
Department of Histopathology, Wythenshawe Hospital.
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MeSH Terms
Adenoma / complications,  pathology*
Cell Differentiation
Ear Neoplasms / complications,  pathology*
Ear, Middle / pathology*
Hearing Loss / etiology

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