Document Detail

Middle cerebral artery peak systolic and ductus venosus velocity waveforms in the hydropic fetus.
MedLine Citation:
PMID:  15661952     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to assess whether Doppler assessment of the middle cerebral artery (MCA) peak systolic velocity (PSV) and ductus venosus (DV) velocity waveforms during sonography of hydropic fetuses may specify the cause of fetal hydrops. METHODS: A level II sonographic examination was performed in 16 hydropic fetuses, and the MCA PSV and DV velocity waveforms were assessed. The MCA PSV values divided hydropic fetuses into anemic (group 1) and nonanemic (group 2) fetuses. In group 2 fetuses, the DV was defined as normal or abnormal. Sonographic examination and Doppler assessment of these vessels specified the cause of hydrops and indicated the use of specific investigations for diagnosing the etiology of fetal hydrops. RESULTS: Seven of 16 fetuses had MCA PSV values greater than 1.50 multiples of the median (group 1). Nine of 16 fetuses had normal MCA PSV values (group 2); among them, 7 of 9 had either absent or reversed flow in the DV, and 2 had a normal DV. In group 1, the cause of fetal anemia was investigated by maternal serum tests, and 5 cordocentesis procedures were performed. In group 2, 7 of 9 fetuses had reversed flow in the DV, which suggested a cardiac abnormality confirmed by echocardiography. Five cordocentesis procedures were performed for fetal karyotype, and in 2 fetuses, the cause of hydrops was idiopathic. CONCLUSIONS: Our data suggest that assessment of the MCA PSV and DV velocity waveforms in the hydropic fetus may further our knowledge of the etiology of hydrops and may indicate which investigations among the many available should be used for diagnosing the cause of fetal hydrops.
Erich Cosmi; Salvatore Dessole; Luisa Uras; Giampiero Capobianco; Donato D'Antona; Alessandra Andrisani; Pietro Litta; Guido Ambrosini
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine     Volume:  24     ISSN:  0278-4297     ISO Abbreviation:  J Ultrasound Med     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-01-21     Completed Date:  2005-05-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211547     Medline TA:  J Ultrasound Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  209-13     Citation Subset:  IM    
Department of Gynecological Science and Reproductive Medicine, University of Padua School of Medicine, Via Giustiniani 3, 35100 Padua, Italy.
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MeSH Terms
Blood Flow Velocity
Gestational Age
Hydrops Fetalis / physiopathology,  ultrasonography*
Middle Cerebral Artery / ultrasonography*
Systole / physiology
Ultrasonography, Doppler*
Ultrasonography, Prenatal*

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