Document Detail

Midaortic syndrome in a premature infant.
MedLine Citation:
PMID:  22670355     Owner:  NLM     Status:  In-Process    
Hypertension is an unusual finding in premature infants and warrants an extensive workup. Well-known causes of hypertension include endocrine, renal and cardiac anomalies. Coarctation of the thoracic aorta, a well-recognized cardiac anomaly leading to hypertension can manifest at various ages including the newborn period. In contrast, midaortic syndrome (MAS), also known as midaortic dysplastic syndrome, is a rare clinical syndrome involving hypoplasia of the abdominal aorta (AA) 1 with varying degrees of narrowing of the visceral branches, often presenting as intractable hypertension. Though there are case reports describing this condition in older children and adults, the diagnosis of MAS can be extremely difficult in neonates, especially in preterm low-birth-weight infants. We describe a rare case of a premature infant who presented with congestive heart failure in utero and intractable hypertension postnatally. This is the youngest reported case of MAS with autopsy confirmation in the literature.
Prakash M Kabbur; Victor Herson; Leslie Wolkoff
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Connecticut medicine     Volume:  76     ISSN:  0010-6178     ISO Abbreviation:  Conn Med     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-06-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372745     Medline TA:  Conn Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  73-5     Citation Subset:  IM    
Department of Pediatrics, Connecticut Children's Medical Center, University of Connecticut School of Medicine, Hartford, USA.
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