Document Detail

Mid-ventricular obstructive hypertrophic cardiomyopathy during pregnancy complicated by preeclampsia and acute myocardial infarction: a case report.
MedLine Citation:
PMID:  21418527     Owner:  NLM     Status:  MEDLINE    
Hypertrophic cardiomyopathy (HCM) with mid-ventricular obstruction (MVO) is a rare condition occurring in 1% of HCM patients. It is characterized by asymmetric left ventricular hypertrophy with MVO and elevated intraventricular pressure gradients. Myocardial infarction has been associated with mid-ventricular obstructive HCM. Briefly, this case presents an unusual clinical scenario where a young pregnant woman complicated by preeclampsia presents with myocardial injury and hemodynamic compromise related to undiagnosed HCM with MVO illustrating hemodynamic challenges created by pregnancy and surgery.
Anand Singla; Steven E Lipshultz; Stacy Fisher
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2011-03-21
Journal Detail:
Title:  Congenital heart disease     Volume:  6     ISSN:  1747-0803     ISO Abbreviation:  Congenit Heart Dis     Publication Date:    2011 May-Jun
Date Detail:
Created Date:  2011-05-23     Completed Date:  2011-09-16     Revised Date:  2012-01-09    
Medline Journal Info:
Nlm Unique ID:  101256510     Medline TA:  Congenit Heart Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  257-61     Citation Subset:  IM    
Copyright Information:
© 2011 Copyright the Authors. Congenital Heart Disease © 2011 Wiley Periodicals, Inc.
Heart Failure and Cardiac Transplant Fellow Texas Heart Institute, Baylor College of Medicine Houston, TX, USA.
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MeSH Terms
Cardiac Myosins / genetics
Cardiomyopathy, Hypertrophic / complications,  diagnosis*,  genetics,  physiopathology,  therapy
Cardiovascular Agents / therapeutic use
Coronary Angiography
Drug Therapy, Combination
Echocardiography, Doppler
Magnetic Resonance Imaging
Myocardial Infarction / diagnosis*,  etiology,  physiopathology,  therapy
Myosin Heavy Chains / genetics
Pre-Eclampsia / diagnosis*,  physiopathology,  therapy
Predictive Value of Tests
Pregnancy Complications, Cardiovascular / diagnosis,  etiology,  physiopathology,  therapy
Radionuclide Ventriculography
Treatment Outcome
Reg. No./Substance:
0/Cardiovascular Agents; 0/MYH7 protein, human; 0/Myosin Heavy Chains; EC 3.6.1.-/Cardiac Myosins

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