Document Detail

Mid-term results of valve replacement with the ATS valve: a seven-year follow up.
MedLine Citation:
PMID:  17578046     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND AIM OF THE STUDY: The ATS open pivot bileaflet valve has been the prosthesis of choice at the authors' hospital since 1997. Herein is presented a retrospective analysis of the mid-term results of valve replacement with the ATS valve prosthesis.
METHODS: Between 1997 and 2005, a total of 280 patients (mean age 58.3 years) underwent valve replacement with the ATS valve; these included 133 aortic valve replacements (AVR), 115 mitral valve replacements (MVR), and 32 double (aortic plus mitral) valve replacements (DVR). Preoperatively, 162 patients (57.9%) were in NYHA functional class II, 97 (34.6%) in class III, 19 (6.8%) in class IV, and two (0.7%) in class V. Atrial fibrillation was detected in 105 patients (37.5%), and significant coronary artery disease was found concomitantly in 13 (4.6%). Postoperative anticoagulant therapy consisting of warfarin and an antiplatelet drug was usually instituted on the first postoperative day, and the International Normalized Ratio maintained between 1.6 and 2.5.
RESULTS: Overall hospital mortality was 3.6% (n = 10). Hospital survivors were followed for a mean period of 4.2 years (maximum 10 years); the total follow up was 1,127.9 patient-years (pt-yr). Follow up was complete for 267 patients (98.9%). Actuarial survival at seven years was 87.1% for AVR, 79.8% for MVR, and 90.1% for DVR. The probability of freedom from valve-related death at seven years was 96.7% for AVR, 94.4% for MVR, and 100% for DVR. The linearized rates for postoperative complications were thromboembolism 1.2%/pt-yr, major bleeding 0.7%/pt-yr, prosthetic valve endocarditis 0.2%/pt-yr, non-structural dysfunction 0.7%/pt-yr, and reoperation 0.5%/pt-yr. Structural valve failure was not encountered.
CONCLUSION: This clinical experience with the ATS open pivot heart valve demonstrated low rates of adverse events and valve-related complications.
Shigeaki Aoyagi; Hidetsugu Hori; Kazuhiro Yoshikawa; Koichi Arinaga; Shuji Fukunaga
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of heart valve disease     Volume:  16     ISSN:  0966-8519     ISO Abbreviation:  J. Heart Valve Dis.     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-06-20     Completed Date:  2007-07-19     Revised Date:  2014-07-29    
Medline Journal Info:
Nlm Unique ID:  9312096     Medline TA:  J Heart Valve Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  267-74     Citation Subset:  IM    
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MeSH Terms
Aortic Valve / surgery*
Endocarditis / etiology
Follow-Up Studies
Heart Valve Diseases / mortality,  surgery
Heart Valve Prosthesis* / adverse effects
Hemorrhage / etiology
Hospital Mortality
Middle Aged
Mitral Valve / surgery*
Prosthesis Failure
Prosthesis-Related Infections / etiology
Retrospective Studies
Thromboembolism / etiology
Thrombosis / etiology
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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