Document Detail

Mid-term outcome after carotid artery stenting depends on presence of coronary artery disease.
MedLine Citation:
PMID:  16581699     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Longer-term outcome of patients following carotid artery revascularization depends predominantly on cardiac events rather than neurological events. AIM: To assess the longer-term outcomes of patients with known coronary artery morphology undergoing carotid artery stenting. METHOD: In a prospective observational study including 549 consecutive patients undergoing carotid artery stenting, a coronary angiography was performed in a single session unless a recent angiogram was available. Following the intervention, patients were followed prospectively to determine neurological events as well as major adverse coronary events (MACE) during long-term follow-up. RESULTS: Coronary artery disease was present in 378 patients including 92 patients without current significant stenosis. The MACE rate was 6.4% in patients without coronary artery disease compared to 28.3% in patients with coronary artery disease (P<0.00001). Cardiac and all-cause mortality were statistically significantly higher in patients with a significant coronary stenosis than in patients without coronary artery disease (P<0.001 and P<0.01). Cardiac mortality and all-cause mortality were 2.3% and 7.6% in patients without coronary artery disease (patient group I), 7.6% and 13.0% in patients with coronary artery disease but no current significant stenosis (patient group II), and 10.5% and 16.1% in patients with significant coronary stenosis (patient group III). Neurological events, however, were distributed equally among the three patient groups. CONCLUSIONS: In the longer term, outcomes in patients undergoing carotid artery stenting depend on concomitant coronary artery disease rather than neurological events, cardiac mortality and even all-cause mortality depending on a significant coronary artery stenosis.
Robert Hofmann; Alex Kypta; Clemens Steinwender; Juergen Kammler; Klaus Kerschner; Michael Grund; Franz Leisch
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of medicine     Volume:  38     ISSN:  0785-3890     ISO Abbreviation:  Ann. Med.     Publication Date:  2006  
Date Detail:
Created Date:  2006-04-03     Completed Date:  2006-08-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8906388     Medline TA:  Ann Med     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  137-43     Citation Subset:  IM    
Cardiovascular Division, City Hospital Linz, Austria.
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MeSH Terms
Carotid Artery, Internal*
Carotid Stenosis / complications*,  surgery
Coronary Angiography
Coronary Artery Disease / complications*,  radiography
Coronary Stenosis / complications*
Disease-Free Survival
Incidental Findings
Long-Term Care

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