| The Microwave-to-Flow Paradigm: Translating High-Temperature Batch Microwave Chemistry to Scalable Continuous-Flow Processes. | |
| | |
MedLine Citation:
|
PMID: 21932289 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The popularity of dedicated microwave reactors in many academic and industrial laboratories has produced a plethora of synthetic protocols that are based on this enabling technology. In the majority of examples, transformations that require several hours when performed using conventional heating under reflux conditions reach completion in a few minutes or even seconds in sealed-vessel, autoclave-type, microwave reactors. However, one severe drawback of microwave chemistry is the difficulty in scaling this technology to a production-scale level. This Concept article demonstrates that this limitation can be overcome by translating batch microwave chemistry to scalable continuous-flow processes. For this purpose, conventionally heated micro- or mesofluidic flow devices fitted with a back-pressure regulator are employed, in which the high temperatures and pressures attainable in a sealed-vessel microwave chemistry batch experiment can be mimicked. |
| | |
Authors:
|
Toma N Glasnov; C Oliver Kappe |
Related Documents
:
|
7840379 - Analysis of nutrient hepatic blood flow after 8-mm versus 16-mm portacaval h-grafts in ... 10791789 - Plasma concentration of urea, ammonia, glutamine around calving, and the relation of he... 10430369 - Decreased hepatic nitric oxide synthesis during liver surgery. 6824999 - Effective liver blood flow: determination by galactose clearance. 2061839 - Blood flow to and the metabolism of glucose and lactate by the liver in vivo in fetal, ... 1989729 - H1 and h2 receptor antagonists and hepatic oxygen supply-demand relationship in pigs. 7658349 - Importance of dermal blood supply and epidermis on the transdermal iontophoretic delive... 947569 - Differences in muscle blood flow in upper and lower extremities of patients after corre... 6097659 - The advantages of hemodilution anesthesia for major liver resection in children. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-9-20 |
Journal Detail:
|
Title: Chemistry (Weinheim an der Bergstrasse, Germany) Volume: - ISSN: 1521-3765 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
|
Created Date: 2011-9-20 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9513783 Medline TA: Chemistry Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
Affiliation:
|
Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, 8010 Graz (Austria), Fax: (+43) 316-380-9840. toma.glasnov@uni-graz.at. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A 5'-Cap for DNA Probes Binding RNA Target Strands.
Next Document: Er(3+) -Doped Anatase TiO(2) Nanocrystals: Crystal-Field Levels, Excited-State Dynamics, Upconversio...