| Microwave-promoted facile and efficient preparation of N-(alkoxycarbonylmethyl) nucleobases--building blocks for peptide nucleic acids. | |
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MedLine Citation:
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PMID: 17851409 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A simple, rapid, and regioselective approach for the synthesis of N-(methoxy-carbonylmethyl)- and N-(n-propoxycarbonylmethyl) nucleobases was developed. By using DMF as the solvent and in the presence of K2CO3 as the base, all the desired products were obtained in moderate yields within 8 min under microwave irradiation. |
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Authors:
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Guirong Qu; Zhiguang Zhang; Haiming Guo; Mingwei Geng; Ran Xia |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2007-03-19 |
Journal Detail:
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Title: Molecules (Basel, Switzerland) Volume: 12 ISSN: 1420-3049 ISO Abbreviation: Molecules Publication Date: 2007 |
Date Detail:
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Created Date: 2007-09-13 Completed Date: 2007-10-23 Revised Date: 2009-10-27 |
Medline Journal Info:
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Nlm Unique ID: 100964009 Medline TA: Molecules Country: Switzerland |
Other Details:
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Languages: eng Pagination: 543-51 Citation Subset: IM |
Affiliation:
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College of Chemistry and Environmental Science, Henan Normal University, Xinxiang 453007, PR China. quguir@163.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Alkylation Cytosine / analogs & derivatives*, chemical synthesis, chemistry Dimethylformamide Microwaves* Peptide Nucleic Acids / chemistry* Purines / chemical synthesis*, chemistry Thymine / analogs & derivatives*, chemical synthesis, chemistry Time Factors Uracil / analogs & derivatives, chemistry |
| Chemical | |
Reg. No./Substance:
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0/Peptide Nucleic Acids; 0/Purines; 65-71-4/Thymine; 66-22-8/Uracil; 68-12-2/Dimethylformamide; 71-30-7/Cytosine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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