Document Detail


Microwave-Assisted Decarboxylative Three-Component Coupling of a 2-Oxoacetic acid, an Amine and an Alkyne.
MedLine Citation:
PMID:  21823621     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A novel and efficient microwave-assisted decarboxylative three-component coupling of a 2-oxoacetic acid, an amine and an alkyne (OA2-coulpling) has been developed. This new multicomponent coupling constitutes an efficient approach for the synthesis of polysubstituted propargylamines in the presence of a catalytic amount of copper(I) catalyst.
Authors:
Huangdi Feng; Denis Semyonovich Ermolat'ev; Gonghua Song; Erik Válery Van der Eycken
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-8
Journal Detail:
Title:  The Journal of organic chemistry     Volume:  -     ISSN:  1520-6904     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985193R     Medline TA:  J Org Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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