Document Detail

Microvenular Hemangioma Presenting With Numerous Bilateral Macules, Patches, and Plaques: A Case Report and Review of the Literature.
MedLine Citation:
PMID:  22722465     Owner:  NLM     Status:  Publisher    
ABSTRACT:: Microvenular hemangioma (MVH) is a rare, slowly growing, benign vascular tumor that typically presents as a solitary enlarging plaque or nodule on the trunk or the extremities of young to middle-aged adults. A minority of MVH present with multiple lesions that are either gradually or suddenly acquired (eruptive MVH). Herein, we report a case of a 53-year-old woman who progressively developed numerous bilateral MVHs presenting as enlarging, blanching, erythematous to violaceous macules, patches, and plaques over the proximal thighs and axillae. Two biopsies exhibited the irregular branching venules with inconspicuous lumina lacking endothelial atypia and associated with dermal fibrosis characteristic of MVH. Immunophenotypically, the endothelium expressed Wilms Tumor 1, CD31, CD34, and erythrocyte-type glucose transporter protein (GLUT-1) GLUT-1 focally and was negative for Human herpes virus 8 and the lymphatic marker D2-40. In addition, numerous dermal spindle cells expressing CD34 and procollagen, putative fibrocytes, surrounded the thickened dermal collagen bundles and small vessels of MVH implicating a reactive/reparative (proliferative) process due to an unrecognized cutaneous injury. A review of MVH summarizing its clinicopathologic findings and its natural history is presented.
Konstantinos Linos; Joan Csaposs; J Andrew Carlson
Related Documents :
11014585 - Efficacy of restaining prostate needle biopsies with high-molecular weight cytokeratin.
20418235 - External quality assessment scheme for parasite serology; a review of the scheme design...
9987445 - Does use of the autopap assisted primary screener improve cytologic diagnosis?
25126435 - Endoscopic co(2) laser horizontal partial laryngectomy in larynx carcinosarcoma.
12143955 - Adrenal adenoma presenting with torsade de pointes--a case report.
8773235 - Congenital annular constricting band: a case report with pseudarthrosis and review of t...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-20
Journal Detail:
Title:  The American Journal of dermatopathology     Volume:  -     ISSN:  1533-0311     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911005     Medline TA:  Am J Dermatopathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
*Department of Pathology and Laboratory Medicine, Albany Medical College, Albany, NY †Upper Hudson Valley Dermatology and Skin Care Center, Castleton, NY.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Microcystic Adnexal Carcinoma Versus Desmoplastic Trichoepithelioma: A Comparative Study.
Next Document:  Expression of Matrix Metalloproteinase-13 and Ki-67 in Nonmelanoma Skin Cancer in Xeroderma Pigmento...