Document Detail


Microvasculature of the pancreas. Relation to pancreatitis.
MedLine Citation:
PMID:  1527446     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Local or generalized alteration of microcirculation may be expected in diseases of the pancreas. Changes may range from increased permeability of capillaries to hemorrhage. Tissue necrosis may result from prolonged ischemia owing to intravascular coagulation and severely impaired blood flow. It is possible to observe early microvascular changes by intravital microscopy. Klar and coworkers have demonstrated by this method that isovolemic hemodilution improves blood flow under conditions that would otherwise lead to tissue damage. This paper presents the basic microcirculation of the pancreas and the changes that accompany pancreatic disease. It emphasizes that concentration on the changes in microcirculation that accompany the early manifestations of pancreatic diseases, particularly pancreatitis, may reveal important clues to their pathogenesis.
Authors:
D E Bockman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International journal of pancreatology : official journal of the International Association of Pancreatology     Volume:  12     ISSN:  0169-4197     ISO Abbreviation:  Int. J. Pancreatol.     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1992-10-22     Completed Date:  1992-10-22     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8703511     Medline TA:  Int J Pancreatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  11-21     Citation Subset:  IM    
Affiliation:
Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta 30912-2000.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Animals
Chronic Disease
Humans
Lymphatic System / anatomy & histology
Microcirculation
Pancreas / blood supply*,  innervation
Pancreatitis / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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