Document Detail


Microvascular skin response to local cooling and body tilt early after digital replantation.
MedLine Citation:
PMID:  10811761     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To elucidate the alteration in cutaneous microvascular reactivity early after replantation (14-21 days), laser Doppler (LD) flow changes evoked by direct and indirect local cooling and head-up body tilt were studied in the replanted digits (n = 10) and compared with those evoked in the healthy contralateral digits of the same patients (n = 10). During the first 3 minutes of direct cooling of the injured hand, LD flow increased significantly compared with the LD flow before cooling, which confirms that moderate vasodilation is the dominant component of the response to local cooling in skin microcirculation in the early period after replantation. During body tilt, LD flow in the healthy contralateral digit decreased significantly in only the first minute, while LD flow in the replanted digit started to decrease in the second minute after tilting; the decrease was significant from the third to the sixth minute. These results are consistent with the hypothesis that increased human skin alpha-adrenergic receptor sensitivity may be present as early as 2 to 3 weeks after replantation.
Authors:
K Cankar; Z M Arnez; Z Finderle; M strucl
Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of hand surgery     Volume:  25     ISSN:  0363-5023     ISO Abbreviation:  J Hand Surg Am     Publication Date:  2000 May 
Date Detail:
Created Date:  2000-08-03     Completed Date:  2000-08-03     Revised Date:  2009-06-08    
Medline Journal Info:
Nlm Unique ID:  7609631     Medline TA:  J Hand Surg Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  552-8     Citation Subset:  IM    
Affiliation:
Institute of Physiology, School of Medicine, University of Ljubljana, Slovenia.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Amputation, Traumatic / surgery*
Analysis of Variance
Cold Temperature*
Female
Finger Injuries / surgery
Fingers / surgery*
Head-Down Tilt*
Humans
Laser-Doppler Flowmetry
Male
Microcirculation / physiology
Middle Aged
Prognosis
Regional Blood Flow
Replantation / methods*
Skin / blood supply*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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