Document Detail


Microvascular ischemia in patients with myotonic dystrophy.
MedLine Citation:
PMID:  10981860     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two women with myotonic dystrophy underwent dipyridamole thallium-201 (201Tl) myocardial perfusion imaging, after which one patient developed flat T waves in lead I and aV(L), and inverted T waves in leads V(2-6). The other patient developed a nonspecific intraventricular block that progressed to complete left bundle branch block and was associated with chest discomfort. Reversible scintigraphic defects were observed in both women. Although there was evidence that suggested myocardial ischemia on the ECG changes and 201Tl scintigraphic findings, coronary angiography demonstrated no significant stenoses in either patient. These findings suggest that microvascular dysfunction may lead to myocardial ischemia and conduction disturbances in patients with myotonic dystrophy.
Authors:
H Itoh; M Shimizu; Y Horita; H Ino; T Taguchi; K Kajinami; K Yagi; D Chujo; H Mabuchi
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  64     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  2000 Sep 
Date Detail:
Created Date:  2000-12-18     Completed Date:  2001-02-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  720-2     Citation Subset:  IM    
Affiliation:
Second Department of Internal Medicine, School of Medicine, Kanazawa University, Japan.
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MeSH Terms
Descriptor/Qualifier:
Electrocardiography
Female
Heart / radionuclide imaging
Heart Conduction System / physiopathology
Humans
Ischemia / etiology,  physiopathology*,  radionuclide imaging
Microcirculation / physiopathology*,  radionuclide imaging
Middle Aged
Myotonic Dystrophy / complications*
Thallium Radioisotopes / diagnostic use
Chemical
Reg. No./Substance:
0/Thallium Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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