Document Detail


Microsporum praecox: molecular identification of a new case and review of the literature.
MedLine Citation:
PMID:  20658321     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
We report a rare case of dermatophytosis due to Microsporum praecox in a 28-year-old female horse rider. The skin lesion was located on the right external malleolus. Microscopic examination of skin scrapings revealed a dermatophyte which was also isolated in culture. The identification of M. praecox was confirmed by molecular biology (sequence analysis of PCR products amplified from internal transcribed spacer regions with universal primers). Combined antifungal therapy with oral terbinafine and topical cyclopiroxolamide resulted in complete remission of the fungal lesion within 1 month. Since 1944, only 29 cases of human M. praecox infection have been reported in the literature. The clinical features and treatment of these cases are reviewed. The prevalence of M. praecox infection is probably underestimated, and systematic molecular identification could improve our understanding of the epidemiology of this fungal dermatosis.
Authors:
Alexandre Alanio; Stéphane Romand; Dominique Penso-Assathiany; Françoise Foulet; Françoise Botterel
Publication Detail:
Type:  Journal Article     Date:  2010-07-25
Journal Detail:
Title:  Mycopathologia     Volume:  171     ISSN:  1573-0832     ISO Abbreviation:  Mycopathologia     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7505689     Medline TA:  Mycopathologia     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  61-5     Citation Subset:  IM    
Affiliation:
Laboratoire de Parasitologie-Mycologie, Hôpital Henri Mondor, (AP-HP) Créteil, Université Paris Est, 51 avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France.
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