| Microscopic structural study of collagen aging in isolated fibrils using polarized second harmonic generation. | |
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MedLine Citation:
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PMID: 23224157 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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ABSTRACT. Polarization resolved second harmonic generation (PSHG) is developed to study, at the microscopic scale, the impact of aging on the structure of type I collagen fibrils in two-dimensional coatings. A ribose-glycated collagen is also used to mimic tissue glycation usually described as an indicator of aging. PSHG images are analyzed using a generic approach of the molecular disorder information in collagen fibrils, revealing significant changes upon aging, with a direct correlation between molecular disorder and fibril diameters. |
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Authors:
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Dora Aït-Belkacem; Marie Guilbert; Muriel Roche; Julien Duboisset; Patrick Ferrand; Ganesh Sockalingum; Pierre Jeannesson; Sophie Brasselet |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of biomedical optics Volume: 17 ISSN: 1560-2281 ISO Abbreviation: J Biomed Opt Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-12-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9605853 Medline TA: J Biomed Opt Country: United States |
Other Details:
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Languages: eng Pagination: 80506-1 Citation Subset: IM |
Affiliation:
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Aix-Marseille Université, Institut Fresnel, CNRS UMR 7249, Ecole Centrale, Marseille, Domaine Universitaire St. Jérôme, 13013 Marseille, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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