Document Detail

Microscopic diversity in oral Kaposi sarcoma.
MedLine Citation:
PMID:  23312917     Owner:  NLM     Status:  In-Data-Review    
Kaposi sarcoma is the most common HIV-associated neoplasm, frequently presenting with oral mucosal involvement. This retrospective study aimed to assess and highlight the histomorphological spectrum of oral Kaposi sarcoma. A total of 135 cases diagnosed between 1990 and 2011 were retrieved from the archives of the Oral and Dental Hospital of the University of Pretoria, South Africa. Following histologic review, each case was placed into 1 of 7 categories based on the predominant pattern of growth. These histologic divisions included lesions designated as solid, lymphangioma-like, telangiectatic, desmoplastic, lymphangiectatic, ecchymotic, and anaplastic. The presence of coexistent pathology was identified in 25 cases, largely represented by superimposed candidiasis. Concomitant cytomegalovirus and non-necrotizing granulomatous inflammation were also observed. Although the prognostic significance of these variants is yet to be determined, the appreciation and recognition of such morphologic diversity remains essential in distinguishing these lesions from possible mimickers.
Belinda K Bunn; Marianne de Vasconcelos Carvalho; Melanie Louw; Pablo A Vargas; Willie F van Heerden
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology and oral radiology     Volume:  115     ISSN:  2212-4411     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101576782     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  241-8     Citation Subset:  D; IM    
Copyright Information:
Copyright © 2013 Elsevier Inc. All rights reserved.
Oral Pathologist, Department of Oral Pathology and Oral Biology, School of Dentistry, Faculty of Health Sciences, University of Pretoria, South Africa.
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