Document Detail

Microscopic Kaposiform Hemangioendothelioma With Extensive Lymphangiomatosis: An Extraordinary Example of an Unusual Entity.
MedLine Citation:
PMID:  23129838     Owner:  NLM     Status:  Publisher    
Kaposiform hemangioendothelioma (KHE) is presently classified as a vascular neoplasm of intermediate malignant potential. The clinical course of large, deep-seated tumors is frequently complicated by consumptive coagulopathy and life-threatening hemorrhage, while superficial tumors tend to behave in an indolent manner, with no known reports of distant metastasis. We describe an unusual example of KHE occurring as an incidental microscopic finding, within a background of extensive lymphangioma-like changes. The patient underwent 4 intralesional excisions over a period of 6 years, and the Kaposiform component accounts for less than 5% of the overall tissue excised. The patient remains clinically well with residual disease 5 years after conservative surgery, and there has been no evidence of regional or distant metastasis. Based on existing literature, it appears doubtful that KHE has any metastatic potential at all, which calls into question the appropriateness of its place in the spectrum of malignant vascular neoplasms.
Irene C Low; Rita Y-T Yang; Pennie J Symmans
Related Documents :
24146338 - Lesions originating within the retrorectal space: a diverse group requiring individuali...
25197668 - Transcription regulation of e-cadherin by zinc finger e-box binding homeobox proteins i...
23403348 - Disseminated glioneuronal tumor with neuropil-like islands of the spinal cord: a distin...
2533348 - Photodynamic therapy--coming of age.
12567188 - The codon 72 polymorphic variants of p53 have markedly different apoptotic potential.
12648598 - Inhibition of paclitaxel-induced apoptosis by the specific cox-2 inhibitor, ns398, in e...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-4
Journal Detail:
Title:  International journal of surgical pathology     Volume:  -     ISSN:  1940-2465     ISO Abbreviation:  Int. J. Surg. Pathol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9314927     Medline TA:  Int J Surg Pathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Desmoplastic Medulloblastoma Arising From an Ovarian Teratoma: A Case Report and Review of the Liter...
Next Document:  Modification of Smoke Toxicant Yields Alters the Effects of Cigarette Smoke Extracts on Endothelial ...