Document Detail


Microscopic Kaposiform Hemangioendothelioma With Extensive Lymphangiomatosis: An Extraordinary Example of an Unusual Entity.
MedLine Citation:
PMID:  23129838     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Kaposiform hemangioendothelioma (KHE) is presently classified as a vascular neoplasm of intermediate malignant potential. The clinical course of large, deep-seated tumors is frequently complicated by consumptive coagulopathy and life-threatening hemorrhage, while superficial tumors tend to behave in an indolent manner, with no known reports of distant metastasis. We describe an unusual example of KHE occurring as an incidental microscopic finding, within a background of extensive lymphangioma-like changes. The patient underwent 4 intralesional excisions over a period of 6 years, and the Kaposiform component accounts for less than 5% of the overall tissue excised. The patient remains clinically well with residual disease 5 years after conservative surgery, and there has been no evidence of regional or distant metastasis. Based on existing literature, it appears doubtful that KHE has any metastatic potential at all, which calls into question the appropriateness of its place in the spectrum of malignant vascular neoplasms.
Authors:
Irene C Low; Rita Y-T Yang; Pennie J Symmans
Related Documents :
6239128 - The effect of cooling on the photodynamic action of hematoporphyrin derivative during i...
22930628 - Anterior skull base surgery.
6229668 - Inability to elicit rapid cytocidal effects on l1210 cells derived from porphyrin-injec...
15756028 - Effect of polyethylene glycol linker chain length of folate-linked microemulsions loadi...
11029488 - Dihydropyrimidine dehydrogenase activity and mrna expression in advanced gastric cancer...
1867358 - Malignant hair matrix tumor ("malignant trichoepithelioma") arising in the setting of m...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-4
Journal Detail:
Title:  International journal of surgical pathology     Volume:  -     ISSN:  1940-2465     ISO Abbreviation:  Int. J. Surg. Pathol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9314927     Medline TA:  Int J Surg Pathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Desmoplastic Medulloblastoma Arising From an Ovarian Teratoma: A Case Report and Review of the Liter...
Next Document:  Modification of Smoke Toxicant Yields Alters the Effects of Cigarette Smoke Extracts on Endothelial ...