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Micropatterned model biological membranes composed of polymerized and fluid lipid bilayers.
MedLine Citation:
PMID:  20408674     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Micropatterned phospholipid bilayers on solid substrates offer an attractive platform for various applications, such as high-throughput drug screening. The authors have developed a photopolymerization-based methodology for generating micropatterned bilayers composed of polymerized and fluid lipid bilayers. Lithographic photopolymerization of a diacetylene-containing phospholipid (DiynePC) allowed facile fabrication of compartmentalized arrays of fluid lipid membranes. Herein, the authors report on the present state of research and discuss on the prospective application of the model membranes.
Authors:
Kenichi Morigaki
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biointerphases     Volume:  3     ISSN:  1559-4106     ISO Abbreviation:  Biointerphases     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2010-04-22     Completed Date:  2010-04-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101275679     Medline TA:  Biointerphases     Country:  United States    
Other Details:
Languages:  eng     Pagination:  FA85     Citation Subset:  -    
Affiliation:
Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Technology (AIST), Ikeda 563-8577, Japan. morigaki-kenichi@aist.go.jp
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