Document Detail


Microparticles--messengers of biological information.
MedLine Citation:
PMID:  20597998     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Endothelial cell apoptosis is a pivotal step in the development of atherosclerotic disease. Regeneration of the damaged endothelium is an attractive therapy option in the prevention and treatment of atherosclerotic disease. Apoptosis is associated with the release of microparticles (MP). Besides their role as marker of cell damage, recent reports have underlined their role as signalling elements in cell-cell communication. In this review, we focus on the emerging role of circulating MP as transmitters of biological information in cardiovascular disease.
Authors:
Friedrich Felix Hoyer; Georg Nickenig; Nikos Werner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cellular and molecular medicine     Volume:  14     ISSN:  1582-4934     ISO Abbreviation:  J. Cell. Mol. Med.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-11-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101083777     Medline TA:  J Cell Mol Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  2250-6     Citation Subset:  IM    
Copyright Information:
© 2010 The Authors Journal compilation © 2010 Foundation for Cellular and Molecular Medicine/Blackwell Publishing Ltd.
Affiliation:
Department of Cardiology, University Hospital Bonn, Bonn, Germany. felix.hoyer@ukb.uni-bonn.de
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