| Micronutrients, birth weight, and survival. | |
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MedLine Citation:
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PMID: 20415580 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Maternal micronutrient requirements during pregnancy increase to meet the physiologic changes in gestation and fetal demands for growth and development. Maternal micronutrient deficiencies are high and coexist in many settings, likely influencing birth and newborn outcomes. The only recommendation for pregnancy currently exists for iron and folic acid use. Evidence is convincing that maternal iron supplementation will improve birth weight and perhaps gestational length. In one randomized trial, iron supplementation during pregnancy reduced child mortality in the offspring compared with the control group. Few other single micronutrients given antenatally, including vitamin A, zinc, and folic acid, have been systematically shown to confer such a benefit. A meta-analysis of 12 trials of multiple micronutrient supplementation compared with iron-folic acid reveals an overall 11% reduction in low birth weight but no effect on preterm birth and perinatal or neonatal survival. Currently, data are unconvincing for replacing supplementation of antenatal iron-folic acid with multiple micronutrients. |
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Authors:
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Parul Christian |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Annual review of nutrition Volume: 30 ISSN: 1545-4312 ISO Abbreviation: Annu. Rev. Nutr. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-21 Completed Date: 2010-10-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8209988 Medline TA: Annu Rev Nutr Country: United States |
Other Details:
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Languages: eng Pagination: 83-104 Citation Subset: IM |
Affiliation:
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Center for Human Nutrition, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA. pchristi@jhsph.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Birth Weight*
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drug effects,
physiology Dietary Supplements Female Humans Infant Mortality Infant, Newborn Maternal Nutritional Physiological Phenomena / physiology* Micronutrients / administration & dosage*, physiology* Nutritional Requirements Pregnancy Pregnancy Outcome Prenatal Nutritional Physiological Phenomena / physiology* |
| Chemical | |
Reg. No./Substance:
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0/Micronutrients |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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