Document Detail

Micronutrient sprinkles add more bioavailable iron to some Kenyan complementary foods: studies using an in vitro digestion/Caco-2 cell culture model.
MedLine Citation:
PMID:  19292749     Owner:  NLM     Status:  MEDLINE    
Iron deficiency anaemia is arguably the most important public health problem in developing countries. In Sub-Saharan Africa, iron deficiency anaemia has largely been attributed to poor infant feeding practices where complementary foods low in iron bioavailability are offered to at-risk infants. Home fortification of complementary foods using micronutrient Sprinkles has been shown to reduce iron deficiency anaemia in many resource-poor settings. In this study, the benefit of using the micronutrient Sprinkles as a home fortificant for some Kenyan complementary foods was assessed using an in vitro Caco-2 cell model. In each case when micronutrient Sprinkles were added to the complementary food, the amount of Caco-2 cell ferritin formation increased. For example, the addition of Sprinkles to corn porridge increased ferritin formation 5-fold from 5.8 to 31.8 ng mg(-1). Therefore, as indicated by the results, micronutrient Sprinkles would be a suitable form of home fortification for Kenyan complementary foods. Their use should be encouraged so as to improve infant feeding practices in Kenya.
Mercy G Lung'aho; Raymond P Glahn
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Maternal & child nutrition     Volume:  5     ISSN:  1740-8709     ISO Abbreviation:  Matern Child Nutr     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-03-18     Completed Date:  2009-06-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101201025     Medline TA:  Matern Child Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  151-8     Citation Subset:  IM    
Department of Food Science, Cornell University, Ithaca, New York, USA.
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MeSH Terms
Biological Availability
Caco-2 Cells
Dietary Supplements
Food, Fortified / analysis
Infant Food / analysis
Infant Nutritional Physiological Phenomena
Iron / administration & dosage*,  analysis,  pharmacokinetics*
Micronutrients / administration & dosage*,  analysis
Zea mays
Reg. No./Substance:
0/Micronutrients; 7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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