| Micronutrient sprinkles add more bioavailable iron to some Kenyan complementary foods: studies using an in vitro digestion/Caco-2 cell culture model. | |
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MedLine Citation:
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PMID: 19292749 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Iron deficiency anaemia is arguably the most important public health problem in developing countries. In Sub-Saharan Africa, iron deficiency anaemia has largely been attributed to poor infant feeding practices where complementary foods low in iron bioavailability are offered to at-risk infants. Home fortification of complementary foods using micronutrient Sprinkles has been shown to reduce iron deficiency anaemia in many resource-poor settings. In this study, the benefit of using the micronutrient Sprinkles as a home fortificant for some Kenyan complementary foods was assessed using an in vitro Caco-2 cell model. In each case when micronutrient Sprinkles were added to the complementary food, the amount of Caco-2 cell ferritin formation increased. For example, the addition of Sprinkles to corn porridge increased ferritin formation 5-fold from 5.8 to 31.8 ng mg(-1). Therefore, as indicated by the results, micronutrient Sprinkles would be a suitable form of home fortification for Kenyan complementary foods. Their use should be encouraged so as to improve infant feeding practices in Kenya. |
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Authors:
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Mercy G Lung'aho; Raymond P Glahn |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Maternal & child nutrition Volume: 5 ISSN: 1740-8709 ISO Abbreviation: Matern Child Nutr Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-03-18 Completed Date: 2009-06-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101201025 Medline TA: Matern Child Nutr Country: England |
Other Details:
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Languages: eng Pagination: 151-8 Citation Subset: IM |
Affiliation:
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Department of Food Science, Cornell University, Ithaca, New York, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biological Availability Caco-2 Cells Diet* Dietary Supplements Digestion* Food, Fortified / analysis Humans Infant Infant Food / analysis Infant Nutritional Physiological Phenomena Iron / administration & dosage*, analysis, pharmacokinetics* Kenya Manihot Micronutrients / administration & dosage*, analysis Panicum Sorghum Zea mays |
| Chemical | |
Reg. No./Substance:
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0/Micronutrients; 7439-89-6/Iron |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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