Document Detail


Micronutrient bioavailability: Dietary Reference Intakes and a future perspective.
MedLine Citation:
PMID:  20200261     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article provides a review of how the challenge of bioavailability was approached in establishing the Dietary Reference Intakes, with a special focus on folic acid, vitamin B-12, beta-carotene, iron, selenium, and zinc, the targeted micronutrients for this workshop. In a future perspective, the necessity of having a clear working definition of bioavailability is emphasized. The bioavailability of micronutrients should be considered, with advantage, under subheadings determined by the broad factors that affect bioavailability. Special emphasis is given to giving greater and specific attention to factors involved in the maintenance of homeostasis. These factors, it is argued, are best considered separately from even a broad definition of bioavailability and have the potential to provide new insights into some micronutrient requirements.
Authors:
K Michael Hambidge
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2010-03-03
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  91     ISSN:  1938-3207     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-21     Completed Date:  2010-05-28     Revised Date:  2011-07-28    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1430S-1432S     Citation Subset:  AIM; IM    
Affiliation:
Department of Pediatrics, Section of Nutrition, University of Colorado Denver, Aurora, CO 80045, USA. michael.hambidge@ucdenver.edu
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MeSH Terms
Descriptor/Qualifier:
Biological Availability*
Calcium, Dietary
Carotenoids / metabolism
Energy Intake / physiology*
Food, Fortified*
Humans
Iron, Dietary
Micronutrients / metabolism*
Nutritional Requirements
Oxalates / metabolism
Phytic Acid / metabolism
Vitamin B 12 / metabolism
Grant Support
ID/Acronym/Agency:
U01 HE040657//PHS HHS
Chemical
Reg. No./Substance:
0/Calcium, Dietary; 0/Iron, Dietary; 0/Micronutrients; 0/Oxalates; 36-88-4/Carotenoids; 68-19-9/Vitamin B 12; 83-86-3/Phytic Acid
Comments/Corrections

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