| Micronutrient-Enriched Rapeseed Oils Improve the Brain Oxidant/Antioxidant System in Rats Fed a High-Fat Diet. | |
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MedLine Citation:
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PMID: 21417278 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The main proposal of this study was to evaluate in vivo whether micronutrient-enriched rapeseed oils obtained using different crushing and refining procedures and characterized by different quantities and qualities of micronutrients (optimized oils) could have any beneficial effect on the antioxidant status of the brain. Sprague-Dawley rats were fed a high-fat diet for 4 weeks. The lipid source consisted of 20% optimized rapeseed oils with different quantities and qualities of micronutrients. The control group received traditional refined rapeseed oil. The experimental optimized oils decreased lipid peroxidation and increased endogenous antioxidant status in parallel with the enhancement of micronutrients. No alteration in acetylcholinesterase activity was induced by the high-fat diet in any experimental group. These results indicate that a regular intake of optimized rapeseed oils can prevent oxidative stress, providing evidence that optimized rapeseed oils could be a functional food with potentially important neuroprotective properties. |
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Authors:
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Serafina Salvati; Lucilla Attorri; Rita Di Benedetto; Stefano Fortuna; Antonella Di Biase |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-3-18 |
Journal Detail:
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Title: Journal of agricultural and food chemistry Volume: - ISSN: 1520-5118 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-3-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0374755 Medline TA: J Agric Food Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Public Veterinary Health and Food Safety and ‡Department of Drug Safety and Evaluation, Istituto Superiore di Sanità , Viale Regina Elena 299, 00161 Rome, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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