Document Detail


Micronodular hyperplasia of type II pneumocytes--a new lung lesion associated with tuberous sclerosis.
MedLine Citation:
PMID:  2071093     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Open lung biopsy in a 38-year-old female with Pringle-Bourneville syndrome and recurrent pneumothorax revealed a micronodular pneumocyte II hyperplasia, a new entity probably associated with the tuberous sclerosis syndrome. The lesion caused an obstruction of the alveolar lymphatic vessels and alveolar ducts, resulting in an emphysema-like picture. This cystic dilation of alveoli and draining lymphatics followed by rupture caused the recurrent pneumothorax. The epithelial pneumocytic nature of the lesion was confirmed by immunohistochemistry and electronmicroscopy.
Authors:
H H Popper; F M Juettner-Smolle; M G Pongratz
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Histopathology     Volume:  18     ISSN:  0309-0167     ISO Abbreviation:  Histopathology     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1991-08-22     Completed Date:  1991-08-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7704136     Medline TA:  Histopathology     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  347-54     Citation Subset:  IM    
Affiliation:
Institute of Pathology, University of Graz, Austria.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biological Markers
Biopsy
Female
Humans
Hyperplasia / etiology,  pathology
Immunohistochemistry
Lung Diseases, Obstructive / etiology,  pathology*
Pneumothorax / diagnosis*,  etiology
Tuberous Sclerosis / complications*
Chemical
Reg. No./Substance:
0/Biological Markers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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