| Micronized flavonoids in pain control after hemorrhoidectomy: a prospective randomized controlled study. | |
| | |
MedLine Citation:
|
PMID: 14605954 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: We conducted a prospective randomized controlled study to evaluate the effect of micronized flavonoid fractions (MFF) on pain after hemorrhoidectomy. METHODS: The subjects were 112 consecutive patients randomly assigned either to receive MFF (group 1) for 1 week or not to receive MFF, as a control (group 2), after hemorrhoidectomy, The severity of pain and the number of intramuscular analgesic injections required were recorded for the first 3 days, then 1 week after hemorrhoidectomy. The number of days that intramuscular analgesic injections were required, hospital stay, and patient satisfaction were also assessed. RESULTS: On postoperative day (POD) 1, there were no significant differences between the parameters of the two groups, but on PODs 2 and 3, both the pain score ( P = 0.033 and P = 0.011, respectively) and the number of patients who required intramuscular analgesic injections were significantly less in group 1 ( P = 0.022 and P = 0.007, respectively). Moreover, the hospital stay was shorter and patient satisfaction was superior in group 1 ( P = 0.001 and P = 0.001, respectively). After 1 week, the pain score and number of intramuscular analgesic injections given were significantly less in group 1 ( P = 0.001 and P = 0.021). CONCLUSION: Using MFF after hemorrhoidectomy reduced the severity of pain and intramuscular analgesic requirement. |
| | |
Authors:
|
Tahsin Colak; Tamer Akca; Musa Dirlik; Arzu Kanik; Ahmet Dag; Suha Aydin |
Related Documents
:
|
11016734 - Radioguided surgery of breast cancer: radiation protection survey. 22125754 - Direct percutaneous alcohol sclerotherapy for venous malformations of head and neck reg... 20569284 - International consensus recommendations on the aesthetic usage of botulinum toxin type ... 18638854 - Injection of hot saline into sympathetic ganglia for palmar hyperhidrosis. 6468544 - A prospective study of lung disease caused by mycobacterium avium/mycobacterium intrace... 6703584 - Long-term follow-up of solitary hemangioma of the choroid. |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
|
Title: Surgery today Volume: 33 ISSN: 0941-1291 ISO Abbreviation: Surg. Today Publication Date: 2003 |
Date Detail:
|
Created Date: 2003-11-07 Completed Date: 2004-03-10 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9204360 Medline TA: Surg Today Country: Japan |
Other Details:
|
Languages: eng Pagination: 828-32 Citation Subset: IM |
Affiliation:
|
Department of Surgery, Mersin Medical Faculty of Mersin University, Tip Fakultesi Hastanesi Zeytinlibahce C, 33079 Mersin, Turkey. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Analgesics / therapeutic use Dose-Response Relationship, Drug Drug Administration Schedule Female Flavonoids / administration & dosage* Follow-Up Studies Hemorrhoids / diagnosis, surgery* Humans Male Middle Aged Pain Measurement Pain, Postoperative / drug therapy*, prevention & control Probability Prospective Studies Reference Values Severity of Illness Index Statistics, Nonparametric Treatment Outcome |
| Chemical | |
Reg. No./Substance:
|
0/Analgesics; 0/Flavonoids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Long-term results of subtotal colectomy with antiperistaltic cecoproctostomy.
Next Document: Less impaired cell-mediated immune response in the murine peritoneal cavity after CO(2) pneumoperito...