Document Detail

Micronization increases vitamin E carrying and releasing abilities of insoluble fiber.
MedLine Citation:
PMID:  18303818     Owner:  NLM     Status:  MEDLINE    
This study was to investigate the effects of micronization on vitamin-carrying capacity and slow-release ability of carambola (starfruit) insoluble fiber (IF) and cellulose using in vitro and in vivomodels. Upon micronization, carambola IF (8.1 microm) underwent structural changes to expose more functional groups in the fiber matrix and to exhibit higher oil-holding capacity ( approximately 20.4-fold). Micronized fibers in forms of fiber-vitamin composites, particularly the micronized carambola IF-vitamin composite, were capable of carrying vitamin E (alpha-tocopherol) up to 9.6-fold over their unmicronized forms and releasing nutrient gradually. Animal studies demonstrated that the adminstration of micronized carambola IF-vitamin composite could maintain the plasma vitamin E of rats at relatively higher levels (2.1-3.6-fold of the initial values) for at least 5 h. The results suggested that micronized fibers, particularly the micronized carambola IF, could be exploited as potential nutrient carriers in food applications and also be used to produce slow-release formulations.
Pang-Kuei Hsu; Po-Jung Chien; Chi-Fai Chau
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-02-27
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  56     ISSN:  0021-8561     ISO Abbreviation:  J. Agric. Food Chem.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-19     Completed Date:  2008-06-11     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2170-4     Citation Subset:  IM    
Department of Food Science and Biotechnology, National Chung Hsing University, 250 Kuokuang Road, Taichung 40227, Taiwan.
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MeSH Terms
Angiosperms / chemistry
Cellulose / chemistry
Chemistry, Physical
Dietary Fiber*
Drug Carriers / administration & dosage,  chemistry*
Particle Size
Physicochemical Phenomena
Rats, Sprague-Dawley
Vitamin E / administration & dosage*,  blood,  pharmacokinetics
Reg. No./Substance:
0/Drug Carriers; 1406-18-4/Vitamin E; 9004-34-6/Cellulose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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