| Microneedle Biosensor: A Method for Direct Label-free Real Time Protein Detection. | |
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MedLine Citation:
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PMID: 23355762 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Here we present the development of an array of electrical micro-biosensors in a microfluidic channel, called microneedle biosensors. A microneedle biosensor is a real-time, label-free, direct electrical detection platform, which is capable of high sensitivity detection, measuring the change in ionic current and impedance modulation, due to the presence or reaction of biomolecules such as proteins and nucleic acids. In this study, we successfully fabricated and electrically characterized the sensors and demonstrated successful detection of target protein. In this study, we used biotinylated bovine serum albumin as the receptor and streptavidin as the target analyte. |
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Authors:
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Rahim Esfandyarpour; Hesaam Esfandyarpour; Mehdi Javanmard; James S Harris; Ronald W Davis |
Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: Sensors and actuators. B, Chemical Volume: 177 ISSN: 0925-4005 ISO Abbreviation: Sens Actuators B Chem Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2013-1-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101149755 Medline TA: Sens Actuators B Chem Country: - |
Other Details:
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Languages: ENG Pagination: 848-855 Citation Subset: - |
Affiliation:
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Center for Integrated Systems, Department of Electrical Engineering, Stanford University ; Stanford Genome Technology Center; 855 California Ave., Palo Alto, CA 94304, USA. |
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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