Document Detail


Microlithiasis: an important cause of "idiopathic" acute pancreatitis?
MedLine Citation:
PMID:  15094703     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Microlithiasis is the underlying cause in a significant proportion of patients with "idiopathic" acute pancreatitis. The mechanism appears to be a relative deficiency of phosphatidylcholine in bile, with fast and extensive cholesterol crystallization as a result. Diagnosis of microlithiasis by microscopic detection of cholesterol crystals in bile is important and should lead to appropriate therapy (cholecystectomy, endoscopic sphincterotomy or ursodeoxycholic acid maintenance therapy).
Authors:
Niels G Venneman; Sigrid E van Brummelen; Gerard P van Berge-Henegouwen; Karel J van Erpecum
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Annals of hepatology     Volume:  2     ISSN:  1665-2681     ISO Abbreviation:  Ann Hepatol     Publication Date:    2003 Jan-Mar
Date Detail:
Created Date:  2004-04-19     Completed Date:  2004-06-08     Revised Date:  2013-05-16    
Medline Journal Info:
Nlm Unique ID:  101155885     Medline TA:  Ann Hepatol     Country:  Mexico    
Other Details:
Languages:  eng     Pagination:  30-5     Citation Subset:  IM    
Affiliation:
Gastrointestinal Research Unit, Depts. of Gastroenterology and Surgery, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Calculi / chemistry,  complications*,  diagnosis,  prevention & control
Cholagogues and Choleretics / therapeutic use
Cholangiopancreatography, Endoscopic Retrograde*
Cholecystectomy
Gallstones / chemistry,  complications*,  diagnosis,  surgery
Humans
Pancreatitis / diagnosis,  etiology*,  surgery
Risk Factors
Ursodeoxycholic Acid / therapeutic use
Chemical
Reg. No./Substance:
0/Cholagogues and Choleretics; 128-13-2/Ursodeoxycholic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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