Document Detail

Microinvasive ductal carcinoma of the breast. Role of axillary lymph node dissection
MedLine Citation:
PMID:  10394511     Owner:  NLM     Status:  MEDLINE    
The role of axillary lymph node dissection for microinvasive ductal carcinoma in situ of the breast was analyzed in a series of 60 consecutive cases. Forty-four cases were subclinical mammographically-detected carcinomas revealed by the clusters of microcalcifications. Although pathologists differ in their criteria for microinvasion, the maximal size considered in this retrospective study was 2 mm. Axillary lymph node involvement was found in 3 cases (i.e. 5%) which harbored poor histologic features: comedocarcinoma subtype, high nuclear grade, and size of the ductal carcinoma in situ greater than 3 cm, requiring total mastectomy. While there is no need for axillary dissection in women with pure ductal carcinoma in situ, the management is quite different in proven microinvasion. Owing to the weakness of prognostic information given by cellular, biochemical and molecular features, instead of lymph node status, axillary dissection is still recommended in microinvasive ductal carcinoma in situ.
G Le Bouëdec; F Penault-Llorca; M de Latour; J Joubert; P Kauffmann; C Pomel; J Dauplat
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Journal de gynécologie, obstétrique et biologie de la reproduction     Volume:  28     ISSN:  0368-2315     ISO Abbreviation:  J Gynecol Obstet Biol Reprod (Paris)     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-08-03     Completed Date:  1999-08-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0322206     Medline TA:  J Gynecol Obstet Biol Reprod (Paris)     Country:  FRANCE    
Other Details:
Languages:  fre     Pagination:  10-6     Citation Subset:  IM    
Service de Chirurgie, Centre Régional de Lutte Contre le Cancer Jean-Perrin, Clermont-Ferrand.
Vernacular Title:
Carcinome canalaire micro-invasif du sein. Place du curage ganglionnaire axillaire.
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MeSH Terms
Breast Neoplasms / pathology*,  surgery
Carcinoma, Ductal, Breast / pathology*,  surgery
Lymph Node Excision*
Middle Aged
Neoplasm Invasiveness
Retrospective Studies
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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