| Microglia-like or microglia: results of the weak silver carbonate staining method of del Rio-Hortega. | |
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MedLine Citation:
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PMID: 22404562 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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We investigated the character and origin of the newly described "microglia-like" cell in the mammalian organ of Corti after aminoglycoside intoxication. We replicated the neomycin-induced ototoxicity model in cochleae of neonatal Sprague-Dawley rats and used their brains as microglia positive controls. The weak silver carbonate staining method of del Rio-Hortega was used to identify the microglia-like cell. The microglia-like cell was confirmed by transmission electron microscope (TEM). Microglia in the brain were stained while rat microglia-like cells in the cochlea were unstained by the weak silver carbonate staining method of del Rio-Hortega. Because the microglia-like cell was unstained by the method of del Rio-Hortega, it is unlikely that the newly found cell is related to microglia. |
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Authors:
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Yucheng Wang; W Wei |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-3-12 |
Journal Detail:
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Title: Biotechnic & histochemistry : official publication of the Biological Stain Commission Volume: - ISSN: 1473-7760 ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-3-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9107378 Medline TA: Biotech Histochem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Otorhinolaryngology Head and Neck Surgery, Eye and ENT Hospital of Fudan University. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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