Document Detail


Microfluidic proportional flow controller.
MedLine Citation:
PMID:  21874096     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Precise flow control in microfluidic chips is important for many biochemical assays and experiments at microscale. While several technologies for controlling fluid flow have been implemented either on- or off-chip, these can provide either high-speed or high-precision control, but seldom could accomplish both at the same time. Here we describe a new on-chip, pneumatically activated flow controller that allows for fast and precise control of the flow rate through a microfluidic channel. Experimental results show that the new proportional flow controllers exhibited a response time of approximately 250 ms, while our numerical simulations suggest that faster actuation down to approximately 50 ms could be achieved with alternative actuation schemes.
Authors:
Harrison Prentice-Mott; Mehmet Toner; Daniel Irimia
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Journal of micromechanics and microengineering : structures, devices, and systems     Volume:  20     ISSN:  1361-6439     ISO Abbreviation:  -     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2011-8-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101243057     Medline TA:  J Micromech Microeng     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-8     Citation Subset:  -    
Affiliation:
Harvard School of Engineering and Applied Sciences, Cambridge, MA 02129, USA.
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
P41 EB002503-07//NIBIB NIH HHS; R21 AI076760-02//NIAID NIH HHS

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