Document Detail


Microfluidic Platforms for Studies of Angiogenesis, Cell Migration, and Cell-Cell Interactions : Sixth International Bio-Fluid Mechanics Symposium and Workshop March 28-30, 2008 Pasadena, California.
MedLine Citation:
PMID:  20069368     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Recent advances in microfluidic technologies have opened the door for creating more realistic in vitro cell culture methods that replicate many aspects of the true in vivo microenvironment. These new designs (i) provide enormous flexibility in controlling the critical biochemical and biomechanical factors that influence cell behavior, (ii) allow for the introduction of multiple cell types in a single system, (iii) provide for the establishment of biochemical gradients in two- or three-dimensional geometries, and (iv) allow for high quality, time-lapse imaging. Here, some of the recent developments are reviewed, with a focus on studies from our own laboratory in three separate areas: angiogenesis, cell migration in the context of tumor cell-endothelial interactions, and liver tissue engineering.
Authors:
Seok Chung; Ryo Sudo; Vernella Vickerman; Ioannis K Zervantonakis; Roger D Kamm
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-1-13
Journal Detail:
Title:  Annals of biomedical engineering     Volume:  -     ISSN:  1521-6047     ISO Abbreviation:  -     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-1-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361512     Medline TA:  Ann Biomed Eng     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
School of Mechanical Engineering, Korea University, Seoul, Korea.
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