| Microfluidic generation of acoustically active nanodroplets. | |
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MedLine Citation:
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PMID: 22467628 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A microfluidic approach for the generation of perfluorocarbon nanodroplets as the primary emulsion with diameters as small as 300-400 nm is described. The system uses a pressure-controlled delivery of all reagents and increased viscosity in the continuous phase to drive the device into an advanced tip-streaming regime, which results in generation of droplets in the sub-micrometer range. Such nanodroplets may be appropriate for emerging biomedical applications. |
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Authors:
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Thomas D Martz; David Bardin; Paul S Sheeran; Abraham P Lee; Paul A Dayton |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2012-03-29 |
Journal Detail:
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Title: Small (Weinheim an der Bergstrasse, Germany) Volume: 8 ISSN: 1613-6829 ISO Abbreviation: Small Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-06-18 Completed Date: 2012-11-05 Revised Date: 2013-03-08 |
Medline Journal Info:
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Nlm Unique ID: 101235338 Medline TA: Small Country: Germany |
Other Details:
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Languages: eng Pagination: 1876-9 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
Affiliation:
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Curriculum of Applied Science & Engineering - Material Science, University of North Carolina, 310 Taylor Hall, CB 7575, Chapel Hill, NC 27599, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acoustics Drug Delivery Systems Equipment Design Fluorocarbons / chemistry Glycerol / chemistry Lymphatic System / drug effects Microfluidic Analytical Techniques* Microfluidics* Microscopy / methods Microscopy, Electron, Transmission / methods Nanotechnology / methods Optics and Photonics / methods Particle Size Pressure Viscosity |
| Grant Support | |
ID/Acronym/Agency:
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R01 EB008733/EB/NIBIB NIH HHS; R01EB008733/EB/NIBIB NIH HHS; R21EB011704/EB/NIBIB NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Fluorocarbons; 56-81-5/Glycerol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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