Document Detail


Microevolutionary studies in nematodes: a beginning.
MedLine Citation:
PMID:  11536293     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Comparisons between related species often allow the detailed genetic analysis of evolutionary processes. Here we advocate the use of the nematode Caenorhabditis elegans (and several other rhabditid species) as model systems for microevolutionary studies. Compared to Drosophila species, which have been a mainstay of such studies, C. elegans has a self-fertilizing mode of reproduction, a shorter life cycle and a convenient cell-level analysis of phenotypic variation. Data concerning its population genetics and ecology are still scarce, however. We review molecular, behavioral and developmental intraspecific polymorphisms for populations of C. elegans, Oscheius sp. 1 and Pristionchus pacificus. Focusing on vulval development, which has been well characterized in several species, we discuss relationships between patterns of variations: (1) for a given genotype (developmental variants), (2) after mutagenesis (mutability), (3) in different populations of the same species (polymorphisms) and (4) between closely related species. These studies have revealed that evolutionary variations between sister species affect those characters that show phenotypic developmental variants, that are mutable and that are polymorphic within species.
Authors:
M Delattre; M A Félix
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  BioEssays : news and reviews in molecular, cellular and developmental biology     Volume:  23     ISSN:  0265-9247     ISO Abbreviation:  Bioessays     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-09-05     Completed Date:  2001-10-11     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8510851     Medline TA:  Bioessays     Country:  England    
Other Details:
Languages:  eng     Pagination:  807-19     Citation Subset:  IM    
Copyright Information:
Copyright 2001 John Wiley & Sons, Inc.
Affiliation:
Institut Jacques Monod, CNRS, Universités de Paris 6 et 7, Tour 43, 2 place Jussieu, 75251 Paris cedex 05, France.
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MeSH Terms
Descriptor/Qualifier:
Animals
Caenorhabditis elegans / genetics
Drosophila / genetics
Evolution*
Genetic Techniques
Genetic Variation
Genotype
Mutagenesis
Nematoda / classification*,  genetics*
Polymorphism, Genetic*

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