| Microencephaloceles: another dual pathology of intractable temporal lobe epilepsy in childhood. | |
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MedLine Citation:
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PMID: 20367340 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Temporal lobe encephaloceles can be associated with temporal lobe epilepsy. The authors report on the case of an adolescent with multiple microencephaloceles, in the anterolateral middle fossa floor, identified at surgery (temporal lobectomy) for intractable partial-onset seizures of temporal origin. Magnetic resonance imaging revealed only hippocampal atrophy. Subdural electrodes demonstrated ictal activity arising primarily from the anterior and lateral temporal lobe, close to the microencephaloceles, spreading to the anterior and posterior mesial structures. Pathological examination revealed diffuse temporal gliosis involving the hippocampus, together with microdysgenesis of the amygdala. The literature on epilepsy secondary to encephaloceles is reviewed and the contribution of the microencephaloceles to the seizure disorder in this patient is discussed. |
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Authors:
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Kristian Aquilina; Dave F Clarke; James W Wheless; Frederick A Boop |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of neurosurgery. Pediatrics Volume: 5 ISSN: 1933-0715 ISO Abbreviation: J Neurosurg Pediatr Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-06 Completed Date: 2010-04-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101463759 Medline TA: J Neurosurg Pediatr Country: United States |
Other Details:
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Languages: eng Pagination: 360-4 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, Frenchay Hospital, Bristol, United Kingdom. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Amygdala / pathology, surgery Cranial Fossa, Middle / pathology, surgery Electroencephalography Encephalocele / complications*, pathology*, surgery Epilepsy, Temporal Lobe / etiology*, pathology*, surgery Female Gliosis / pathology, surgery Hippocampus / pathology, surgery Humans Magnetic Resonance Imaging Meningocele / complications*, pathology*, surgery Temporal Lobe / pathology, surgery |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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